|
Mutation Information
|
Mutation Site
|
L65F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
33324377
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2020 |
|
Journal
|
Frontiers in microbiology |
|
Title
|
High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer. |
|
Author
|
Hirose Y,Yamaguchi-Naka M,Onuki M,Tenjimbayashi Y,Tasaka N,Satoh T,Tanaka K,Iwata T,Sekizawa A,Matsumoto K,Kukimoto I |
|
Evidence
|
Of the 10 coding-region variations, nine were non-synonymous or missense substitutions, generating variant forms of viral proteins: E1 Q142K, E1 M207I, E1 L262V, E2 D153Y, E2 R302T, E2 A357T, E7 L65F, L1 E52* (*, nonsense mutation), and L2 N147D.
|
|
|
HPV Mutation Detail Information