Mutation Information
Mutation Site
|
L64A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
Australia |
Literature Information
PubMed PMID
|
17630831
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2007 |
Journal
|
PLoS pathogens |
Title
|
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase. |
Author
|
Belzile JP,Duisit G,Rougeau N,Mercier J,Finzi A,Cohen EA |
Evidence
|
We analyzed whether the L64A and Q65R mutations in this domain of Vpr could abrogate binding to VPRBP.
|
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