|
Mutation Information
|
Mutation Site
|
L62I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E4 |
|
Amino acid_Mutation
|
C3515A |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Romania |
Literature Information
|
PubMed PMID
|
25143263
|
|
Disease
|
Cervical carcinoma;
Squamous-cell carcinoma;
Cervical intraepithelial neoplasia
|
|
Published Year
|
2014 |
|
Journal
|
Archives of virology |
|
Title
|
Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients. |
|
Author
|
Plesa A,Anton G,Iancu IV,Diaconu CC,Huica I,Stanescu AD,Socolov D,Nistor E,Popa E,Stoian M,Botezatu A |
|
Evidence
|
These substitutions result in amino acid changes (T22A, P36T, A43K, Q53R, L62I and L62P, respectively) and seem to be important in malignancy progression.
|
|
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HPV Mutation Detail Information