HIV Mutation Detail Information

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Mutation Information

Mutation Site	L565M
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp41

Literature Information

PubMed PMID	16054592
Published Year	2005
Journal	Biochemical and biophysical research communications
Title	L565M mutation in HIV-1 glycoprotein 41 stabilizes the coiled-coil structure.
Author	Yamamoto D,Li GM,Ikuta K,Goto T
Evidence	L565M mutation in HIV-1 glycoprotein 41 stabilizes the coiled-coil structureN-terminal and C-terminal heptad repeats (NHR and CHR) of HIV type 1 (HIV-1) glycoprotein 41 are known to be regions directly related to cell fusion during virus attack, and their complex core constructs a coiled-coil structure in the fusion process.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation