|
Mutation Information
|
Mutation Site
|
L45M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp41 |
|
Viral Reference
|
K03455.1
|
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
24616600
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
Journal of Korean medical science |
|
Title
|
Characterization of Gp41 polymorphisms in the fusion peptide domain and T-20 (Enfuvirtide) resistance-associated regions in Korean HIV-1 isolates. |
|
Author
|
Jang DH,Yoon CH,Choi BS,Chung YS,Kim HY,Chi SG,Kim SS |
|
Evidence
|
Minor T-20 resistance mutations such as L45M (1.2%), N126K (1.2%), and E137K (6.7%) were detected, but the critical T-20 resistance mutations were not detected in the gp41 HR1 and HR2 regions.
|
|
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HIV Mutation Detail Information