|
Mutation Information
|
Mutation Site
|
L44M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp41 |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
K03455.1
|
|
Country
|
southern China |
Literature Information
|
PubMed PMID
|
33166562
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
Virus research |
|
Title
|
HIV-1 gp41 genetic diversity and enfuvirtide resistance-associated mutations among enfuvirtide-naïve patients in southern China. |
|
Author
|
Chang L,Zhao J,Guo F,Ji H,Zhang L,Jiang X,Wang L |
|
Evidence
|
One major DRM (L44 M), many secondary DRMs (including N126 K, E137 K, S138A), and lots of polymorphisms were found in the study, which have been proved to elevate resistance to ENF.
|
|
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HIV Mutation Detail Information