|
Mutation Information
|
Mutation Site
|
L44I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E5 |
|
Amino acid_Mutation
|
C3979A |
|
Genotype/Subtype
|
HPV-16 |
|
Viral Reference
|
AY686583.1
|
|
Country
|
France |
Literature Information
|
PubMed PMID
|
33633240
|
|
Disease
|
Squamous-cell carcinoma
|
|
Published Year
|
2021 |
|
Journal
|
Scientific reports |
|
Title
|
Episomal HPV16 responsible for aggressive and deadly metastatic anal squamous cell carcinoma evidenced in peripheral blood. |
|
Author
|
Péré H,Vernet R,Pernot S,Pavie J,Robillard N,Puech J,Lameiras S,Lucas ML,Nicolas A,Badoual C,Rance B,Bélec L,Weiss L,Wack M,Veyer D |
|
Evidence
|
Single base substitutions at positions 1522, 3979 and 6219 created E1-T220S, E5-L44I and L1-V220I mutant proteins, respectively.
|
|
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HPV Mutation Detail Information