|
Mutation Information
|
Mutation Site
|
L42F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AB014394.1
|
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
29434654
|
|
Disease
|
Hepatocellular carcinoma;
Occult HBV infection
|
|
Published Year
|
2018 |
|
Journal
|
Infectious agents and cancer |
|
Title
|
Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection. |
|
Author
|
Hatazawa Y,Yano Y,Okada R,Tanahashi T,Hayashi H,Hirano H,Minami A,Kawano Y,Tanaka M,Fukumoto T,Murakami Y,Yoshida M,Hayashi Y |
|
Evidence
|
The minor populations of variants harbouring the W4R, L30S, Q118R/Stop, N123D and S124F/P mutations in the pre-S region and the L21F/S and L42F/S mutations in the S region were detected more frequently in OBI-related HCC than in HBsAg-positive HCC.
|
|
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HBV Mutation Detail Information