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Mutation Information
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Mutation Site
|
L422A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
Literature Information
|
PubMed PMID
|
31943114
|
|
Published Year
|
2020 |
|
Journal
|
Nucleic acids research |
|
Title
|
Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase. |
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Author
|
Nguyen PDM,Zheng J,Gremminger TJ,Qiu L,Zhang D,Tuske S,Lange MJ,Griffin PR,Arnold E,Chen SJ,Zou X,Heng X,Burke DH |
|
Evidence
|
Alanine scanning revealed decreased inhibition by the aptamer for mutants P420A, L422A and K424A.
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HIV Mutation Detail Information