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Mutation Information
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Mutation Site
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L406P |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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EBNA3A |
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Viral Reference
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NC007605.1
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Country
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Guangzhou;China |
Literature Information
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PubMed PMID
|
30546078
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Disease
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Extranodal natural killer T-cell lymphoma;
Nasopharyngeal carcinoma;
Gastric carcinoma
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Published Year
|
2019 |
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Journal
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Leukemia |
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Title
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Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma. |
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Author
|
Peng RJ,Han BW,Cai QQ,Zuo XY,Xia T,Chen JR,Feng LN,Lim JQ,Chen SW,Zeng MS,Guo YM,Li B,Xia XJ,Xia Y,Laurensia Y,Chia BKH,Huang HQ,Young KH,Lim ST,Ong CK,Zeng YX,Bei JX |
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Evidence
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Notably, 21 of these epitopes with significant enrichment in NKTCL samples were restricted to six EBV genes, including EBNA3A (G373D, F325L, I333K, L406P, S412R, H464R, M466R, T585I, and A588P), EBNA3B (A399S, V400L, V417L, K424T, Y662D, and K663E), EBNA3C (P916S), BARF1 (V29A), BCRF1 (V6M), and BNRF1 (G456R, S497G, and A1292T).
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EBV Mutation Detail Information