HIV Mutation Detail Information

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Mutation Information

Mutation Site	L33F
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs
Country	USA

Literature Information

PubMed PMID	30148406
Disease	HIV infection/AIDS
Published Year	2018
Journal	AIDS research and human retroviruses
Title	Prevalence of Darunavir Resistance in the United States from 2010 to 2017.
Author	Brown K,Stewart L,Whitcomb JM,Yang D,Nettles RE,Lathouwers E
Evidence	The most common individual darunavir RAMs were L33F (identified in 4.3% of samples in 2010 and 2.4% of samples in 2017;p = .001), I84 V (3.4% and 1.5%, respectively;p = .003), and V32I (2.6% and 1.3%;p = .006);the least common darunavir RAM, L76V, was identified in 0.4% of samples in 2010 and 0.3% of samples in 2017 (p = .083;Fig. 2A).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation