Mutation Information
Mutation Site
|
L319R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tax |
Viral Reference
|
AB038239
|
Literature Information
PubMed PMID
|
21552325
|
Published Year
|
2011 |
Journal
|
PLoS pathogens |
Title
|
NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ. |
Author
|
Zhi H,Yang L,Kuo YL,Ho YK,Shih HM,Giam CZ |
Evidence
|
TaxV89A and TaxL319R, L320S (M47) are deficient in HTLV-1 LTR trans-activation, but competent in NF-kappaB activation.
|
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