Mutation Information
Mutation Site
|
L319R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tax |
Literature Information
PubMed PMID
|
10766811
|
Published Year
|
2000 |
Journal
|
The Journal of biological chemistry |
Title
|
p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex. |
Author
|
Harrod R,Kuo YL,Tang Y,Yao Y,Vassilev A,Nakatani Y,Giam CZ |
Evidence
|
The M47 mutant (L319R, L320S) protein, which has previously been shown to interact with p300/CBP, by contrast, failed to form complexes with P/CAF and is impaired in LTR trans-activation.
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