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Mutation Information
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Mutation Site
|
L319R |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tax |
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Combined Mutation
|
tax.L319R+tax.L320S |
Literature Information
|
PubMed PMID
|
10567539
|
|
Published Year
|
1999 |
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Journal
|
Molecular and cellular biology |
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Title
|
PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner. |
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Author
|
Jiang H,Lu H,Schiltz RL,Pise-Masison CA,Ogryzko VV,Nakatani Y,Brady JN |
|
Evidence
|
Tax mutant M47 (L319R-L320S) is mutated at a position adjacent to TaxS318A. M47 is an important mutant in that it fails to activate HTLV-1 transcription and is defective for transformation
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HTLV1 Mutation Detail Information