|
Mutation Information
|
Mutation Site
|
L28F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Amino acid_Mutation
|
A647G |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
21593270
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2011 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Human papillomavirus type 16 variant analysis of E6, E7, and L1 [corrected] genes and long control region in [corrected] cervical carcinomas in patients in northeast China. |
|
Author
|
Shang Q,Wang Y,Fang Y,Wei L,Chen S,Sun Y,Li B,Zhang F,Gu H |
|
Evidence
|
Forty-four (84.62%) patients showed six mutation sites for the E7 gene, of which two, A645C and A647G, were missense mutations: asparagine→serine (N29S) and leucine→phenylalanine (L28F).
|
|
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HPV Mutation Detail Information