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Mutation Information
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Mutation Site
|
L283I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
NRTIs;NNRTIs |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
23144802
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Screening for and verification of novel mutations associated with drug resistance in the HIV type 1 subtype B(') in China. |
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Author
|
Li H,Geng Q,Guo W,Zhuang D,Li L,Liu Y,Bao Z,Liu S,Li J |
|
Evidence
|
The 9 mutations M41L, D67N, K70R, K103N, Y181C, M184V, T215Y, L283I and N348I resulted in resistance to NRTIs or NNRTIs, but the impact of 7 mutations at 6 positions (D123E, V292I, K366R, T369A, T369V, A371V and I375V) on antiviral drug response was unknown.
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HIV Mutation Detail Information