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Mutation Information
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Mutation Site
|
L23F |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Vpr |
Literature Information
|
PubMed PMID
|
15312229
|
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Published Year
|
2004 |
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Journal
|
Retrovirology |
|
Title
|
Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae. |
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Author
|
Yao XJ,Rougeau N,Duisit G,Lemay J,Cohen EA |
|
Evidence
|
Four amino acids Glu21, Leu23, Glu25 and Ala30 were separately changed to Lys or Phe (E21K, L23F, E25K and A30F) in order to disrupt the amphipaticity of the first alpha-helix .
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HIV Mutation Detail Information