|
Mutation Information
|
Mutation Site
|
L234I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
U46016;
AY242579-AY242597;
KU319672-KU319798;
AY772699;
AF067155;
U52953;
AX149771 |
|
Relevant Drug
|
etravirine(ETR);doravirine (DOR);efavirenz (EFV);nevirapine (NPV);rilpivirine (RPV) |
|
Country
|
Ethiopia |
Literature Information
|
PubMed PMID
|
32993693
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Retrovirology |
|
Title
|
Increased HIV-1 pretreatment drug resistance with consistent clade homogeneity among ART-naive HIV-1 infected individuals in Ethiopia. |
|
Author
|
Kiros M,Alemayehu DH,Geberekidan E,Mihret A,Maier M,Abegaz WE,Mulu A |
|
Evidence
|
Both CPR tool and IAS-USA algorithms were concordant in identifying five NNRTIs resistance-associated mutations: K103N in one patient (1.96%), Y188L, and H221Y in another patient (1.96%), K101E in one patient (1.96%), and V106A in another patient (1.96%).
|
|
|
HIV Mutation Detail Information