|
Mutation Information
|
Mutation Site
|
L228R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Asia;Sub-saharan Africa;Europe;North America |
Literature Information
|
PubMed PMID
|
31774913
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I. |
|
Author
|
Gregson J,Rhee SY,Datir R,Pillay D,Perno CF,Derache A,Shafer RS,Gupta RK |
|
Evidence
|
The following NNRTI mutations were also associated: A98G, L100I, K103R, V108I, Y181C, Y188L, G190A, P225H, L228R, and M230L.
|
|
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HIV Mutation Detail Information