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Mutation Information
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Mutation Site
|
L21R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
27650283
|
|
Disease
|
HBV infection
|
|
Published Year
|
2017 |
|
Journal
|
Journal of hepatology |
|
Title
|
Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA. |
|
Author
|
Xiang KH,Michailidis E,Ding H,Peng YQ,Su MZ,Li Y,Liu XE,Dao Thi VL,Wu XF,Schneider WM,Rice CM,Zhuang H,Li T |
|
Evidence
|
Some mutations (e.g. sE2G, sL21R, sG24K, sT47A/K, sC69stop (sC69*), sL95W, sL98V, and sG145R) negatively correlated with serum HBsAg levels.
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HBV Mutation Detail Information