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EBV Mutation Detail Information

> L218S Search Result


Mutation Information
Mutation Site L218S
Mutation Type Amino acid level
Gene/Protein/Region Type BZLF1
Literature Information
PubMed PMID 9123876
Published Year 1997
Journal Virology
Title The bZip dimerization domain of the Epstein-Barr virus BZLF1 (Z) protein mediates lymphoid-specific negative regulation.
Author Hong Y,Holley-Guthrie E,Kenney S
Evidence As reported before, two Z proteins (Z214R/218R andZ214S/218S) containing mutations within the interface of Z214S/218S) containing mutations within the interface of the coiled-coil helix lost dimerization ability, as well as interaction with p65 (Fig. 1C, Z214R/218R data not shown) (Flemington and Speck, 1991; Gutschet al.,1994).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation