EBV Mutation Detail Information

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Mutation Information

Mutation Site	L214A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BZLF1

Literature Information

PubMed PMID	19144704
Published Year	2009
Journal	Journal of virology
Title	Interaction of Epstein-Barr virus BZLF1 C-terminal tail structure and core zipper is required for DNA replication but not for promoter transactivation.
Author	McDonald CM,Petosa C,Farrell PJ
Evidence	The BZLF1 mutant proteins all gave similar levels of protein expression (measured by the incorporation of [35S]Met) when translated in vitro in reticulocyte lysate (Fig. 2A), and all apart from K207A/L214A gave a measureable shift in the EMSA (Fig. 2B).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation