HIV Mutation Detail Information

> L210W Search Result


Mutation Information
Mutation Site L210W
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug 3'-azido-3'-deoxythymidine
Literature Information
PubMed PMID 32747359
Published Year 2020
Journal Antimicrobial agents and chemotherapy
Title Nucleocapsid Protein Precursors NCp9 and NCp15 Suppress ATP-Mediated Rescue of AZT-Terminated Primers by HIV-1 Reverse Transcriptase.
Author Árquez MA,Martín-Alonso S,Gorelick RJ,Scott WA,Acosta-Hoyos AJ,Menéndez-Arias L
Evidence In HIV-1, development of resistance to AZT (3'-azido-3'-deoxythymidine) is mediated by the acquisition of thymidine analogue resistance mutations (TAMs) (i.e., M41L, D67N, K70R, L210W, T215F/Y, and K219E/Q) in the viral reverse transcriptase (RT).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation