Mutation Information
Mutation Site
|
L205V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
D |
Literature Information
PubMed PMID
|
11481624
|
Disease
|
Fulminant hepatitis B
|
Published Year
|
2001 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis. |
Author
|
Kalinina T,Riu A,Fischer L,Will H,Sterneck M |
Evidence
|
The two mutations present at the C-terminal end (S204Rand L205V; construct M8; Fig. 1) of the variant S-proteins alsoled to an approximately 30% reduction of secretion.
|
|
|