|
Mutation Information
|
Mutation Site
|
L192F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
21503906
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
Journal of medical virology |
|
Title
|
Clinical course and predictive factors of virological response in long-term lamivudine plus adefovir dipivoxil combination therapy for lamivudine-resistant chronic hepatitis B patients. |
|
Author
|
Aizawa M,Tsubota A,Fujise K,Tatsuzawa K,Kono M,Hoshina S,Tajiri H |
|
Evidence
|
In the surface region overlapped with Pol/RT region, some amino acid substitutions were detected: rtA181A/V and sL173L/F, rtA200V and sL192F in case 1, rtV173L and sE164D in case 2, rtM204I and sW196L in cases 1 and 2, and rtM204V and sI195M in case 3.
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HBV Mutation Detail Information