Mutation Information
Mutation Site
|
L183F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tax |
Literature Information
PubMed PMID
|
17535428
|
Published Year
|
2007 |
Journal
|
Retrovirology |
Title
|
HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex. |
Author
|
Merling R,Chen C,Hong S,Zhang L,Liu M,Kuo YL,Giam CZ |
Evidence
|
The other five mutants (V24E, C36Y, G61R, P92L, and L183F) were excluded from the reporter assays because of either the drastic amino acid alterations caused by the mutations or the existence of alternative amino acid substitution in the same position.
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