EBV Mutation Detail Information

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Mutation Information

Mutation Site	L178M
Mutation Type	Amino acid level
Gene/Protein/Region Type	LMP1
Viral Reference	V01555.2
Country	Swiss

Literature Information

PubMed PMID	22384168
Disease	B-cell lymphoma; T-cell lymphoma; Hodgkin lymphoma
Published Year	2012
Journal	PloS one
Title	Genetic diversity of EBV-encoded LMP1 in the Swiss HIV Cohort Study and implication for NF-Κb activation.
Author	Zuercher E,Butticaz C,Wyniger J,Martinez R,Battegay M,Boffi El Amari E,Dang T,Egger JF,Fehr J,Mueller-Garamvögyi E,Parini A,Schaefer SC,Schoeni-Affolter F,Thurnheer C,Tinguely M,Telenti A,Rothenberger S,Swiss HIV Cohort Study.
Evidence	Four polymorphisms L29V, V43L, D46N and I68L are unique to A2 and three, I137L, L178M and E328A, are unique to CAO, which also contains two additional direct repeats (Figure S2).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation