|
Mutation Information
|
Mutation Site
|
L176V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
Ayw |
Literature Information
|
PubMed PMID
|
10385663
|
|
Disease
|
HBV infection
|
|
Published Year
|
1999 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation. |
|
Author
|
Tillmann HL,Trautwein C,Bock T,Böker KH,Jäckel E,Glowienka M,Oldhafer K,Bruns I,Gauthier J,Condreay LD,Raab HR,Manns MP |
|
Evidence
|
The seventh patient (R02) showed no new mutation at position aa195, but selected mutationsoutside the YMDD motif, which led to amino acid changes ataa140 and aa176 (S140I and L176V) of the S-protein (Tables8 and 11).
|
|
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HBV Mutation Detail Information