|
Mutation Information
|
Mutation Site
|
L176* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Relevant Drug
|
entecavir (ETV) |
Literature Information
|
PubMed PMID
|
18435459
|
|
Disease
|
HBV infection
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance. |
|
Author
|
Baldick CJ,Tenney DJ,Mazzucco CE,Eggers BJ,Rose RE,Pokornowski KA,Yu CF,Colonno RJ |
|
Evidence
|
The sV175F, sL176V, sL176stop, and sV194F HBsAg changes found in clinical isolates are represented within the engineered ETVr panel (Supplementary Table 1)
|
|
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HBV Mutation Detail Information