Mutation Information
Mutation Site
|
L173F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Literature Information
PubMed PMID
|
22314422
|
Published Year
|
2012 |
Journal
|
Journal of hepatology |
Title
|
Decreased infectivity of nucleoside analogs-resistant hepatitis B virus mutants. |
Author
|
Billioud G,Pichoud C,Parent R,Zoulim F |
Evidence
|
Because of the overlap between the viral polymerase and envelope genes, the rtV173L, rtA181V, rtA181T, rtM204V, and rtM204I polymerase substitutions are associated with sE164D, sL173F, sW172Stop, s195M, and s196L/S/Stop mutations in the S domain of the three envelope proteins, respectively (Fig. 1).
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