Mutation Information
Mutation Site
|
L172Q |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Literature Information
PubMed PMID
|
19014951
|
Published Year
|
2009 |
Journal
|
Journal of molecular biology |
Title
|
Defining the DNA substrate binding sites on HIV-1 integrase. |
Author
|
Dolan J,Chen A,Weber IT,Harrison RW,Leis J |
Evidence
|
Twelve of the fifteen amino acid exchanges that affect LTR recognition in the processing reaction were combined into a single construct (V72W S153R K160D I161R G163R Q164V V165L H171K L172Q D229I S230E D253N) and purified from the soluble fraction.
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