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Mutation Information
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Mutation Site
|
L165F |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PreS |
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Country
|
China |
Literature Information
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PubMed PMID
|
27835694
|
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Disease
|
Occult HBV infection
|
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Published Year
|
2016 |
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Journal
|
PloS one |
|
Title
|
Occult HBV Infection in Immunized Neonates Born to HBsAg-Positive Mothers: A Prospective and Follow-Up Study. |
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Author
|
Lu Y,Liu YL,Nie JJ,Liang XF,Yan L,Wang FZ,Zhai XJ,Liu JX,Zhu FC,Chang ZJ,Li J |
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Evidence
|
Importantly, 3 mutations (S101L, L165F, S96S/A) located in known T-/B-cell epitopes in Pre-S region. Identical aa substitutions in at least one HBV subgenome were found for 4 (80.0%) mother-child pairs (Table 2).
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HBV Mutation Detail Information