Mutation Information
Mutation Site
|
L159F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tax |
Literature Information
PubMed PMID
|
17535428
|
Published Year
|
2007 |
Journal
|
Retrovirology |
Title
|
HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex. |
Author
|
Merling R,Chen C,Hong S,Zhang L,Liu M,Kuo YL,Giam CZ |
Evidence
|
Like wild-type tax, many of them (C23W, A108T, L159F, and L235F) transactivate both the HTLV-LTR and the NF-kappaB reporters.
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