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Mutation Information
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Mutation Site
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L142A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Small T |
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Country
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America |
Literature Information
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PubMed PMID
|
29696010
|
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Disease
|
Merkel cell carcinoma
|
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Published Year
|
2018 |
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Journal
|
Frontiers in microbiology |
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Title
|
Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1. |
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Author
|
Velásquez C,Amako Y,Harold A,Toptan T,Chang Y,Shuda M |
|
Evidence
|
Then, codon-optimized wild-type MCV sT and the amino acid substitution mutants including L114P, LSD, as well as L142A were inserted into pLenti TRE.MCS EF.Puro-2A-rTet by unique AgeI and SbfI restriction sites.
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MCV Mutation Detail Information