Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Mutation Detail Information

> L131S Search Result


Mutation Information
Mutation Site L131S
Mutation Type Amino acid level
Gene/Protein/Region Type Tax
Viral Reference AB038239
Literature Information
PubMed PMID 21552325
Published Year 2011
Journal PLoS pathogens
Title NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.
Author Zhi H,Yang L,Kuo YL,Ho YK,Shih HM,Giam CZ
Evidence By contrast, TaxH43Q and TaxT130A, L131S (M22) are defective in NF-kappaB activation, but are able to trans-activate the HTLV-1 LTR. Finally, TaxK85A mutant is inactive for both.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation