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Mutation Information
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Mutation Site
|
L131S |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tax |
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Combined Mutation
|
tax.L131S+.130A |
Literature Information
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PubMed PMID
|
14645559
|
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Published Year
|
2003 |
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Journal
|
Journal of virology |
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Title
|
The central region of human T-cell leukemia virus type 1 Tax protein contains distinct domains involved in subunit dimerization. |
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Author
|
Basbous J,Bazarbachi A,Granier C,Devaux C,Mesnard JM |
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Evidence
|
Moreover, the Tax mutants M22 (T130A and L131S) and M29 (K189A and R190S), with amino acid substitutions located in DD1 and DD2, respectively, were found to be impaired in Tax self-association.
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HTLV1 Mutation Detail Information