HIV Mutation Detail Information

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Mutation Information
Mutation Site L124S
Mutation Type Amino acid level
Gene/Protein/Region Type Vif
Literature Information
PubMed PMID 32471198
Published Year 2020
Journal Viruses
Title Structural Insights into APOBEC3-Mediated Lentiviral Restriction.
Author Delviks-Frankenberry KA,Desimmie BA,Pathak VK
Evidence Vif residues 116-131 within the H108-C114-C133-H139 motif act as a cullin box and mutations of Vif I120S and L124S impaired the Vif-Cul5 interaction (Figure 4).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation