HIV Mutation Detail Information

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Mutation Information
Mutation Site L116Q
Mutation Type Amino acid level
Gene/Protein/Region Type Gp120
Viral Reference K03455.1
Relevant Drug fostemsavir
Literature Information
PubMed PMID 32160290
Disease HIV infection/AIDS
Published Year 2020
Journal The Journal of antimicrobial chemotherapy
Title Identification of gp120 polymorphisms in HIV-1 B subtype potentially associated with resistance to fostemsavir.
Author Bouba Y,Berno G,Fabeni L,Carioti L,Salpini R,Aquaro S,Svicher V,Perno CF,Ceccherini-Silberstein F,Santoro MM
Evidence RESULTS: The prevalence of fostemsavir resistance mutations was as follows: L116Q (0.05%), S375H/M/T (0.55%/1.35%/17.73%, the latter being far less relevant in determining resistance), M426L (7.56%), M434I (4.21%) and M475I (1.65%).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation