Mutation Information
Mutation Site
|
L114P |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Small T |
Country
|
America |
Literature Information
PubMed PMID
|
29696010
|
Disease
|
Merkel cell carcinoma
|
Published Year
|
2018 |
Journal
|
Frontiers in microbiology |
Title
|
Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1. |
Author
|
Velásquez C,Amako Y,Harold A,Toptan T,Chang Y,Shuda M |
Evidence
|
Then, codon-optimized wild-type MCV sT and the amino acid substitution mutants including L114P, LSD, as well as L142A were inserted into pLenti TRE.MCS EF.Puro-2A-rTet by unique AgeI and SbfI restriction sites.
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