|
Mutation Information
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Mutation Site
|
L10V |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
|
PubMed PMID
|
27039930
|
|
Published Year
|
2016 |
|
Journal
|
Biochemistry |
|
Title
|
Binding of Clinical Inhibitors to a Model Precursor of a Rationally Selected Multidrug Resistant HIV-1 Protease Is Significantly Weaker Than That to the Released Mature Enzyme. |
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Author
|
Park JH,Sayer JM,Aniana A,Yu X,Weber IT,Harrison RW,Louis JM |
|
Evidence
|
Conservative substitutions L10V and L10I in PR22 and PRS17 respectively, are classified as minor resistance mutations.
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HIV Mutation Detail Information