HIV Mutation Detail Information

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Mutation Information

Mutation Site	L10I
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Genotype/Subtype	B
Viral Reference	K03455.1
Relevant Drug	nelfinavir (NFV);saquinavir (SQV);atazanavir (ATV);indinavir (IDV)
Country	Poland

Literature Information

PubMed PMID	28167814
Disease	HIV infection/AIDS
Published Year	2017
Journal	Medical science monitor : international medical journal of experimental and clinical research
Title	Prevalence of Transmitted Drug-Resistance Mutations and Polymorphisms in HIV-1 Reverse Transcriptase, Protease, and gp41 Sequences Among Recent Seroconverters in Southern Poland.
Author	Smoleń-Dzirba J,Rosińska M,Kruszyński P,Bratosiewicz-Wąsik J,Wojtyczka R,Janiec J,Szetela B,Beniowski M,Bociąga-Jasik M,Jabłonowska E,Wąsik TJ,The Cascade Collaboration In EuroCoord A
Evidence	More than 10% of protease sequences harbored 1 of the following mutations: L10I, G16E, M36L, I64L, I64V, and A71V;whereas over 5% contained D60E, A71T or L89M.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation