HIV Mutation Detail Information

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Mutation Information
Mutation Site L10F
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Relevant Drug NRTIs
Country China
Literature Information
PubMed PMID 33252379
Disease HIV infection/AIDS
Published Year 2020
Journal Chinese medical journal
Title Efficacy and safety of the long-acting fusion inhibitor albuvirtide in antiretroviral-experienced adults with human immunodeficiency virus-1: interim analysis of the randomized, controlled, phase 3, non-inferiority TALENT study.
Author Su B,Yao C,Zhao QX,Cai WP,Wang M,Lu HZ,Chen YY,Liu L,Wang H,He Y,Zheng YH,Li LH,Chen JF,Yu JH,Zhu B,Zhao M,Sun YT,Lun WH,Xia W,Sun LJ,Dai LL,Jiang TY,Wang MX,Zheng QS,Peng HY,Wang Y,Lu RJ,Hu JH,Xing H,Shao YM,Xie D,Zhang T,Zhang FJ,Wu H,TALENT Study Team.
Evidence One patient in the NRTI group developed both major (I50V and V82A) and minor protease resistance mutations (L33F, Q58E, and L10F).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation