Mutation Information
Mutation Site
|
L10F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Relevant Drug
|
PIs |
Literature Information
PubMed PMID
|
28645089
|
Published Year
|
2017 |
Journal
|
Journal of molecular graphics & modelling |
Title
|
Drug Resistance Mechanism of L10F, L10F/N88S and L90M mutations in CRF01_AE HIV-1 protease: Molecular dynamics simulations and binding free energy calculations. |
Author
|
Vasavi CS,Tamizhselvi R,Munusami P |
Evidence
|
In this work, we examined the effect of non active site mutations L10F, L10F/N88S and L90M with nelfinavir using molecular dynamics simulation and binding free energy calculations.
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