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Mutation Information
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Mutation Site
|
L100I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
rilpivirine (RPV) |
Literature Information
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PubMed PMID
|
32701823
|
|
Disease
|
HIV infection/AIDS
|
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Published Year
|
2020 |
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Journal
|
Journal of acquired immune deficiency syndromes (1999) |
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Title
|
Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) From Dolutegravir (DTG)+F/TAF or DTG+F/Tenofovir Disoproxil Fumarate (TDF) in the Presence of Pre-existing NRTI Resistance. |
|
Author
|
Acosta RK,Willkom M,Andreatta K,Liu H,Martin R,Parvangada A,Martin H,Collins S,White KL |
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Evidence
|
Primary NNRTI-R substitutions were L100I, K101E/P, K103N/S, V106A/M, V108I, E138A/G/K/Q/R, V179L, Y181C/I/V, Y188C/H/L, G190A/E/Q/S, H221Y, P225H, F227C, and M230I/L in RT.
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HIV Mutation Detail Information