Mutation Information
Mutation Site
|
L100I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
efavirenz (EFV);nevirapine (NVP) |
Country
|
China |
Literature Information
PubMed PMID
|
32500372
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
Virus genes |
Title
|
Retrospective analysis of HIV-1 drug resistance mutations in Suzhou, China from 2009 to 2014. |
Author
|
Song Y,Hu J,He J,Dong C,Yuan Y,Li Y,Li R,Ya X |
Evidence
|
Two of the mutations, M230L and L100I, which confer a high level of resistance efavirenz (EFV) and nevirapine (NVP) used as NNRTIs for first-line antiretroviral therapy (ART), were detected in this study.
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