|
Mutation Information
|
Mutation Site
|
L100I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.K103N+rt.L100I+rt.T215E+rt.T215D+pr.I47V+pr.V32I |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
|
Country
|
Croatia |
Literature Information
|
PubMed PMID
|
31754119
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Scientific reports |
|
Title
|
Analysis of HIV-1 diversity, primary drug resistance and transmission networks in Croatia. |
|
Author
|
Oroz M,Begovac J,Planinić A,Rokić F,Lunar MM,Zorec TM,Beluzić R,Korać P,Vugrek O,Poljak M,Lepej SŽ |
|
Evidence
|
The most frequent NRTI mutations were: T215S (7.4%), L210W (2.7%), T215D (1.7%) and M41L (1.2%). Resistance to NNRTIs was determined in 27/403 (6.7%) cases, with mutations K101E (3.7%), K103N (2.5%) and L100I (1.9%) most frequently observed.
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HIV Mutation Detail Information