|
Mutation Information
|
Mutation Site
|
L100I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
emtricitabine (FTC) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
30503324
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
The lancet. HIV |
|
Title
|
Acquisition of tenofovir-susceptible, emtricitabine-resistant HIV despite high adherence to daily pre-exposure prophylaxis: a case report. |
|
Author
|
Cohen SE,Sachdev D,Lee SA,Scheer S,Bacon O,Chen MJ,Okochi H,Anderson PL,Kearney MF,Coffey S,Scott H,Grant RM,Havlir D,Gandhi M |
|
Evidence
|
The HIV genotype revealed M184V, L74V, L100I and K103N mutations in reverse transcriptase (RT);the phenotype showed susceptibility to TDF and resistance to FTC.
|
|
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HIV Mutation Detail Information