HIV Mutation Detail Information

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Mutation Information
Mutation Site L100I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NNRTIs
Literature Information
PubMed PMID 20102272
Disease HIV infection/AIDS
Published Year 2010
Journal The Journal of infectious diseases
Title Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients.
Author Halvas EK,Wiegand A,Boltz VF,Kearney M,Nissley D,Wantman M,Hammer SM,Palmer S,Vaida F,Coffin JM,Mellors JW
Evidence By contrast, baseline sequences from NNRTI-naïve subject 5N and 12N containing P225H and L100I, respectively, did not cluster with the predominant resistant variants at failure (Fig 2B–C).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation