Mutation Information
Mutation Site
|
L100I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Country
|
Japan |
Literature Information
PubMed PMID
|
17194486
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2007 |
Journal
|
Antiviral research |
Title
|
Drug-resistant HIV-1 prevalence in patients newly diagnosed with HIV/AIDS in Japan. |
Author
|
Gatanaga H,Ibe S,Matsuda M,Yoshida S,Asagi T,Kondo M,Sadamasu K,Tsukada H,Masakane A,Mori H,Takata N,Minami R,Tateyama M,Koike T,Itoh T,Imai M,Nagashima M,Gejyo F,Ueda M,Hamaguchi M,Kojima Y,Shirasaka T,Kimura A,Yamamoto M,Fujita J,Oka S,Sugiura W |
Evidence
|
Twenty-three cases, including three recently infected patients, were infected with HIV-1 having major drug-resistance mutations, including M41L, D67N, L100I, K103N, V106A, M184I, M184V, L210W, and revertant mutations at the 215 codon in reverse transcriptase and M46I in protease encoding regions.
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