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Mutation Information
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Mutation Site
|
K88A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tax |
Literature Information
|
PubMed PMID
|
9710589
|
|
Published Year
|
1998 |
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Journal
|
Molecular and cellular biology |
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Title
|
An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300. |
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Author
|
Harrod R,Tang Y,Nicot C,Lu HS,Vassilev A,Nakatani Y,Giam CZ |
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Evidence
|
Site-directed mutagenesis of residues in this domain (R82A, K85A, K88A, and V89A) resulted in proteins which failed to transactivate from the HTLV-1 LTR in vivo.
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HTLV1 Mutation Detail Information